Research

Problems sleeping – need some help?

The University of Oxford, in collaboration with Big Health Ltd, is conducting an online study on insomnia.

Most people with insomnia have not only poor sleep, but also problematic daytime effects after a bad night. Therefore, the aim of the study is to find out whether digital Cognitive Behavioural Therapy (that is by web and mobile) can improve health, quality of life and wellbeing as well as poor sleep.

The study is suitable for adults aged 18 years and above who have persistent problems getting to sleep and/ or staying asleep.

For further information about the study and whether or not this might be suitable for you please go to: www.sleepio.com/research/dials or contact:

Dr. Annemarie Luik
Email address: annemarie.luik@ndcn.ox.ac.uk
Phone: +44 (0)1865 618665
Postal address: Dr. Annemarie Luik, Sleep & Circadian Neuroscience Institute, Nuffield Department of Clinical Neurosciences, University of Oxford, Sir William Dunn School of Pathology, South Parks Road, OX1 3RE, UK.

Professor Colin Espie
Email address: colin.espie@ndcn.ox.ac.uk
Postal address: Prof. Colin Espie, Sleep & Circadian Neuroscience Institute, Nuffield Department of Clinical Neurosciences, University of Oxford, Sir William Dunn School of Pathology, South Parks Road, OX1 3RE, UK.


Published papers

  • Espie, C.A., Kyle, S.D, Williams, C., Ong, J.C., Douglas, N.J., Hames, P., Brown, J.S.L. (). A randomized, placebo-controlled, trial of online Cognitive Behavioral Therapy for chronic Insomnia Disorder delivered via an automated media-rich web application. SLEEP 35, 769-781.
  • Espie., C.A., Kyle, S.D., Hames, P., Cyhlarova E., Benzeval, M. (). The daytime impact of DSM-5 Insomnia Disorder: comparative analysis of insomnia subtypes from the Great British Sleep Survey (n=11,129) Journal of Clinical Psychiatry 73, e1478-e1484.
  • Espie, C.A., Hames P., McKinstry, B. (). Use of the internet and mobile media for delivery of cognitive-behavioral insomnia therapy. Sleep Medicine Clinics 8, 407-419.
  • Espie, C.A., Kyle, S.D., Hames, P., Gardani, M., Fleming, L., Cape, J. (). The Sleep Condition Indicator: a clinical screening tool to evaluate Insomnia Disorder. BMJ Open 4:e004183.
  • Espie, C.A., Kyle, S.D., Miller, C.B., Ong, J.C., Hames, P., Fleming, L. (). Attribution, cognition and psychopathology in persistent Insomnia Disorder: outcome and mediation analysis from a randomized placebo-controlled trial of online Cognitive Behavioral Therapy. Sleep Medicine 15(8):913-917.
  • McGrath, E.R., Espie, C.A., Murphy, A.W., Newell, J., Power, A., Madden, S., Byrne, M., O’Donnell, M.J. (). Sleep to lower elevated blood pressure: study protocol for a randomized controlled trial. Trials 15(1), 393.
  • Espie, C.A., Kyle, S.D., Gehrman, P.R., Ong, J.C., Hames, P. (). Tailoring cognitive–behavioural therapy for insomnia to specific needs: a personalised behavioural medicine approach. The European Sleep Medicine Textbook. Edited by P. Peigneux, C.Bassetti and Z. Dogas. (Wiley).
  • Pillai V., Anderson J.R., Cheng P., Bazan L., Bostock S., Espie C.A., Roth T., Drake C.L. (). The Anxiolytic effects of cognitive behavior therapy for insomnia: preliminary results from a web-delivered protocol. Journal of Sleep Medicine Disorders 2(2): 1017.
  • Freeman, D., Sheaves, B., Goodwin, G.M., Yu, L.M., Harrison, P.J., Emsley, R.,Bostock, S., Foster, R.G., Wadekar, V., Hinds, C., Espie, C.A. (). Effects of cognitive behavioural therapy for insomnia on the mental health of university students: study protocol for a randomized controlled trial. Trials 16, 236.
  • Coulson, N.S., Smedley, R., Bostock, S., Kyle, S.D., Gollancz, R., Luik, A.I., Hames, P., Espie, C.A. (). The pros and cons of getting engaged: reflections on the utility of an online social community embedded within digital Cognitive Behavioural Therapy for insomnia: survey among users. Journal of Medical Internet Research, 18: e88.
  • Espie, C.A., Luik, A.I., Cape, J., Drake, C.L., Siriwardena, A.N., Ong, J.C., Gordon, C., Bostock, S., Hames, P., Nisbet, M., Sheaves, B., Foster, R.G., Freeman, D., Costa-Font, J., Emsley, R., Kyle, S.D. (). Digital Cognitive Behavioural Therapy for Insomnia versus sleep hygiene education: the impact of improved sleep on functional health, quality of life and psychological well-being. Study protocol for a randomised controlled trial. Trials 17, 257.
  • Bostock, S., Luik, A.I., Espie, C.A. (). Sleep and productivity benefits of digital Cognitive Behavioral Therapy for Insomnia: a randomized controlled trial conducted in the workplace environment. Journal of Occupational and Environmental Medicine 58, 683-689.
  • Palagini, L., Ragno, G., Caccavale, L., Gronchi, A., Terzaghi, M., Mauri, M., Kyle, S.D., Espie, C.A., Manni, R. (). Italian validation of the Sleep Condition Indicator: A clinical screening tool to evaluate Insomnia Disorder according to DSM-5 criteria. International Journal of Psychophysiolology 98, 435-440.
  • Luik, A.I., Bostock, S., Chisnall, L., Kyle, S.D., Lidbetter, N., Baldwin, N., Espie, C.A. (). Treating depression and anxiety with digital Cognitive Behavioural Therapy for insomnia: a real world NHS evaluation using standardized outcome measures. Behavioural and Cognitive Psychotherapy, published online 26 July.
  • Pinheiro, M.B., Ho, K.K., Ferreira, M.L., Refshauge, K.M., Grunstein, R., Hopper, J.L., Maher, C.G., Koes, B.W., Ordoñana, J.R., Ferreira, P.H. (). Efficacy of a sleep quality intervention in people with low back pain: protocol for a feasibility randomized co-twin controlled trial. Twin Research and Human Genetics 19, 492-501.
  • Barnes, C.M., Miller, J.A., Bostock, S. (). Helping employees sleep well: effects of cognitive behavioral therapy for insomnia on work outcomes. Journal of Applied Psychology, published online 3 October.
  • Wong, M.L., Lau, K.N.T., Espie, C.A., Luik, A.I., Kyle, S.D. Lau, E.Y.Y. (). Psychometric properties of the Sleep Condition Indicator and Insomnia Severity Index in the evaluation of insomnia disorder. Sleep Medicine, published online 22 October.

See further research papers published by Professor Espie


Published abstracts

  • Espie, C.A., Gollancz, R., Hames, P., Espie, A., Creanor, V., Kyle, S.D. (). Integrating social networking into online CBT for insomnia: a descriptive analysis of user behavior and user benefits. SLEEP 36, Suppl. A209.
  • Espie, C.A., Kyle, S.D., Gollancz, R., Hames, P. (). What components of online CBT do people with insomnia use in practice? SLEEP 36, Suppl. A231.
  • Edinger, J.D., Simmons, B., Goelz, K., Bostock, S., Espie, C.A. (). A pilot test of an online cognitive behavioral insomnia therapy for patients with comorbid insomnia and sleep apnea. SLEEP 38, suppl. A236.
  • Drake, C.L., Bostock, S., Espie, C.A. Singh, M., Cheng, P., Anderson, J.R., Pillai, V. (). Anxiolytic effects of cognitive behavior therapy for insomnia: preliminary results from an internet-based protocol. SLEEP 38, suppl. A229.
  • Espie, C.A., Kyle, S.D., Williams, C., Brown, J.S., Ong, J.C., Douglas, N.J., Hames, P. (). A randomized, placebo-controlled, trial of cognitive behavioural therapy for chronic insomnia disorder delivered via an automated media-rich web application. SLEEP 35, suppl. A215.
  • Espie, C.A., Bostock, S., Kyle, S.D., Paluzzi, B., Hames, P. (). Who benefits from online CBT for insomnia? Factors associated with change in sleep efficiency in a large online treatment cohort. SLEEP 37, suppl. A205.

Conference presentations

  • Espie, C.A., Bostock, S., Kyle, S.D., Paluzzi, B., Hames, P. Associations between insomnia phenotype and chronicity with weekly treatment response during online CBT­I: observations within a large online treatment cohort. Presented at SLEEP 2014, Minneapolis, published in SLEEP 37, Suppl. A176 .
  • Bostock, S., Gollancz, R., Paluzzi, B., Hames, P., Espie, C.A. Challenging the 1% rule: an observational study of online community engagement in users of a digital sleep improvement programme. Presented at ISRII Meeting, Valencia, .
  • Coulson, N., Smedley, R., Bostock, S., Kyle, S.D., Gollancz, R., Hames, P., Espie, C.A. The pros and cons of getting engaged: users’ perspectives on the therapeutic role of Sleepio’s online community. Presented at ISRII Meeting, Valencia, .
  • Espie, C.A. The contribution of interactive sleep apps to engagement with and care of people with persistent sleep problems: experience since the launch of the sleepio app. Presented at SLEEP, Seattle, .

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