Research

Published papers

  • Espie, C.A., Kyle, S.D, Williams, C., Ong, J.C., Douglas, N.J., Hames, P., Brown, J.S.L. (). A randomized, placebo-controlled, trial of online Cognitive Behavioral Therapy for chronic Insomnia Disorder delivered via an automated media-rich web application. SLEEP 35, 769-781.
  • Espie., C.A., Kyle, S.D., Hames, P., Cyhlarova E., Benzeval, M. (). The daytime impact of DSM-5 Insomnia Disorder: comparative analysis of insomnia subtypes from the Great British Sleep Survey (n=11,129) Journal of Clinical Psychiatry 73, e1478-e1484.
  • Espie, C.A., Hames P., McKinstry, B. (). Use of the internet and mobile media for delivery of cognitive-behavioral insomnia therapy. Sleep Medicine Clinics 8, 407-419.
  • Espie, C.A., Kyle, S.D., Hames, P., Gardani, M., Fleming, L., Cape, J. (). The Sleep Condition Indicator: a clinical screening tool to evaluate Insomnia Disorder. BMJ Open 4:e004183.
  • Espie, C.A., Kyle, S.D., Miller, C.B., Ong, J.C., Hames, P., Fleming, L. (). Attribution, cognition and psychopathology in persistent Insomnia Disorder: outcome and mediation analysis from a randomized placebo-controlled trial of online Cognitive Behavioral Therapy. Sleep Medicine 15(8):913-917.
  • McGrath, E.R., Espie, C.A., Murphy, A.W., Newell, J., Power, A., Madden, S., Byrne, M., O’Donnell, M.J. (). Sleep to lower elevated blood pressure: study protocol for a randomized controlled trial. Trials 15(1), 393.
  • Espie, C.A., Kyle, S.D., Gehrman, P.R., Ong, J.C., Hames, P. (). Tailoring cognitive–behavioural therapy for insomnia to specific needs: a personalised behavioural medicine approach. The European Sleep Medicine Textbook. Edited by P. Peigneux, C.Bassetti and Z. Dogas. (Wiley).
  • Pillai V., Anderson J.R., Cheng P., Bazan L., Bostock S., Espie C.A., Roth T., Drake C.L. (). The Anxiolytic effects of cognitive behavior therapy for insomnia: preliminary results from a web-delivered protocol. Journal of Sleep Medicine Disorders 2(2): 1017.
  • Freeman, D., Sheaves, B., Goodwin, G.M., Yu, L.M., Harrison, P.J., Emsley, R.,Bostock, S., Foster, R.G., Wadekar, V., Hinds, C., Espie, C.A. (). Effects of cognitive behavioural therapy for insomnia on the mental health of university students: study protocol for a randomized controlled trial. Trials 16, 236.
  • Coulson, N.S., Smedley, R., Bostock, S., Kyle, S.D., Gollancz, R., Luik, A.I., Hames, P., Espie, C.A. (). The pros and cons of getting engaged: reflections on the utility of an online social community embedded within digital Cognitive Behavioural Therapy for insomnia: survey among users. Journal of Medical Internet Research, 18: e88.
  • Espie, C.A., Luik, A.I., Cape, J., Drake, C.L., Siriwardena, A.N., Ong, J.C., Gordon, C., Bostock, S., Hames, P., Nisbet, M., Sheaves, B., Foster, R.G., Freeman, D., Costa-Font, J., Emsley, R., Kyle, S.D. (). Digital Cognitive Behavioural Therapy for Insomnia versus sleep hygiene education: the impact of improved sleep on functional health, quality of life and psychological well-being. Study protocol for a randomised controlled trial. Trials 17, 257.
  • Bostock, S., Luik, A.I., Espie, C.A. (). Sleep and productivity benefits of digital Cognitive Behavioral Therapy for Insomnia: a randomized controlled trial conducted in the workplace environment. Journal of Occupational and Environmental Medicine 58, 683-689.
  • Palagini, L., Ragno, G., Caccavale, L., Gronchi, A., Terzaghi, M., Mauri, M., Kyle, S.D., Espie, C.A., Manni, R. (). Italian validation of the Sleep Condition Indicator: A clinical screening tool to evaluate Insomnia Disorder according to DSM-5 criteria. International Journal of Psychophysiolology 98, 435-440.
  • Pinheiro, M.B., Ho, K.K., Ferreira, M.L., Refshauge, K.M., Grunstein, R., Hopper, J.L., Maher, C.G., Koes, B.W., Ordoñana, J.R., Ferreira, P.H. (). Efficacy of a sleep quality intervention in people with low back pain: protocol for a feasibility randomized co-twin controlled trial. Twin Research and Human Genetics 19, 492-501.
  • Wong, M.L., Lau, K.N.T., Espie, C.A., Luik, A.I., Kyle, S.D. Lau, E.Y.Y. (). Psychometric properties of the Sleep Condition Indicator and Insomnia Severity Index in the evaluation of insomnia disorder. Sleep Medicine 33, 76-81.
  • Luik, A.I., Bostock, S., Chisnall, L., Kyle, S.D., Lidbetter, N., Baldwin, N., Espie, C.A. (). Treating depression and anxiety with digital Cognitive Behavioural Therapy for insomnia: a real world NHS evaluation using standardized outcome measures. Behavioural and Cognitive Psychotherapy 45, 91-96.
  • Barnes, C.M., Miller, J.A., Bostock, S. (). Helping employees sleep well: effects of cognitive behavioral therapy for insomnia on work outcomes. Journal of Applied Psychology 102, 104-113.
  • McGrath, E.R., Espie, C.A., Power, A., Murphy, A.W., Newell, J., Kelly, C., Duffy, N., Gunning, P., Gibson, I., Bostock, S., O’Donnell, M.J. (). Sleep to lower elevated blood pressure: a randomized controlled trial (SLEPT). American Journal of Hypertension 30, 319-327.
  • Luik, A.I., Kyle, S.D., Espie, C.A. (). Digital Cognitive Behavioral Therapy (dCBT) for Insomnia: a state-of-the-science review. Current Sleep Medicine Reports 3, 48-56.
  • Bayard, S., Lebrun, C., Maudarbocus, K.H., Schellaert, V., Joffre, A., Ferrante, E., Le Louedec, M., Cournoulat, A., Gély-Nargeot, M.C., Luik A.I. (). Validation of a French version of the Sleep Condition Indicator: a clinical screening tool for insomnia disorder according to DSM-5 criteria. Journal of Sleep Research, published online 26 May.
  • Kyle, S.D., Hurry, M., Emsley, R., Luik, A.I., Omlin, X., Spiegelhalder, K., Espie, C.A., Sexton, C.E. (). Effects of digital Cognitive Behavioural Therapy for Insomnia on cognitive function: study protocol for a randomised controlled trial. Trials 18, 281.
  • Elison, S., Ward, J., Williams, C., Espie, C.A., Davies, G., Dugdale, S., Ragan, K., Chisnall, L., Lidbetter, N., Smith, K. (). Feasibility of a UK community-based, eTherapy mental health service in Greater Manchester: repeated-measures and between-groups study of ‘Living Life to the Full Interactive’, ‘Sleepio’ and ‘Breaking Free Online’ at ‘Self Help Services’. BMJ Open 7, e016392.
  • Freeman, D., Sheaves, B., Goodwin, G.M., Yu, L.M., Nickless, A., Harrison, P.J., Emsley, R., Luik, A.I., Foster, R.G., Wadekar, V., Hinds, C., Gumley, A., Jones, R., Lightman, S., Jones, S., Bentall, R., Kinderman, P., Rowse, G., Brugha, T., Blagrove, M., Gregory, A.M., Fleming, L., Walklet, E., Glazebrook, C., Davies, E.B., Hollis, C., Haddock, G., John, B., Coulson, M., Fowler, D., Pugh, K., Cape, J., Moseley, P., Brown, G., Hughes, C., Obonsawin, M., Coker, S., Watkins, E., Schwannauer, M., MacMahon, K., Siriwardena, A.N., Espie, C.A. (). The effects of improving sleep on mental health (OASIS): a randomised controlled trial with mediation analysis. Lancet Psychiatry, 4 (10) 749-758
  • Espie, C.A., Farias Machado, P., Carl, J.R., Kyle S.D., Cape, J., Siriwardena, A.N., & Luik, A.I. (). The Sleep Condition Indicator: reference values derived from a sample of 200,000 adults. Journal of Sleep Research, published online 29 November.
  • Denis, D., Eley, T.C., Rijsdijk, F., Zavos, H.M.S., Keers, R., Espie, C.A., Luik, A.I., Badini, I., Deerveeuw, S., Romero, A., Hodsoll, J., & Gregory, A.M. (). Sleep Treatment Outcome Predictors (STOP) Pilot Study: a protocol for a randomised controlled trial examining predictors of change of insomnia symptoms and associated traits following cognitive behavioural therapy for insomnia in an unselected sample. BMJ Open, 7(11):3017177
  • Luik, A.I., Farias Machado, P., & Espie, C.A. (). Delivering digital cognitive behavioral therapy for insomnia at scale: does using a wearable device to estimate sleep influence therapy? npj Digital Medicine, 1(1)

See further research papers published by Professor Espie


Published abstracts

  • Espie, C.A., Gollancz, R., Hames, P., Espie, A., Creanor, V., Kyle, S.D. (). Integrating social networking into online CBT for insomnia: a descriptive analysis of user behavior and user benefits. SLEEP 36, Suppl. A209.
  • Espie, C.A., Kyle, S.D., Gollancz, R., Hames, P. (). What components of online CBT do people with insomnia use in practice? SLEEP 36, Suppl. A231.
  • Edinger, J.D., Simmons, B., Goelz, K., Bostock, S., Espie, C.A. (). A pilot test of an online cognitive behavioral insomnia therapy for patients with comorbid insomnia and sleep apnea. SLEEP 38, suppl. A236.
  • Drake, C.L., Bostock, S., Espie, C.A. Singh, M., Cheng, P., Anderson, J.R., Pillai, V. (). Anxiolytic effects of cognitive behavior therapy for insomnia: preliminary results from an internet-based protocol. SLEEP 38, suppl. A229.
  • Espie, C.A., Kyle, S.D., Williams, C., Brown, J.S., Ong, J.C., Douglas, N.J., Hames, P. (). A randomized, placebo-controlled, trial of cognitive behavioural therapy for chronic insomnia disorder delivered via an automated media-rich web application. SLEEP 35, suppl. A215.
  • Espie, C.A., Bostock, S., Kyle, S.D., Paluzzi, B., Hames, P. (). Who benefits from online CBT for insomnia? Factors associated with change in sleep efficiency in a large online treatment cohort. SLEEP 37, suppl. A205.
  • Cheng, P., Fellman-Couture, C., Ahmedani, C., Tallent, G., Arendt, J., Roehrs, T., Roth, T., Drake, C., (). CBT-I for menopause related insomnia also reduces depression severity. SLEEP 40, suppl. A405.
  • Drake, C., Cheng, P., Luik, A.I., Peterson, E., Joseph, C., Tallent, G., Tran, K., Ahmedani, B., Roehrs, T., Roth, T. (). Preliminary data for the sleep to prevent evolving affective disorders (SPREAD) trial. SLEEP 40, suppl. A131.
  • Crawford, M.R., Espie, C.A., Luik, A.I., Taylor, H.L., Burgess, H.J., Ong, J.C. (). Women with insomnia and debilitating migraines: Sequential administration of online treatment – The WINDSOR study. SLEEP 40, suppl. A125.
  • Luik, A.I., Farias Machado, P., Carl, J., Espie, C.A. (). Normative references for the Sleep Condition Indicator: Derivations from a random sample of 200,000 completers. SLEEP 40, suppl. A116.
  • Luik, A.I., Farias Machado, P., Espie, C.A. (). Digital Cognitive Behavioural Therapy for insomnia in the real world: Does using a wearable device help? Frontiers in Public Health. Conference Abstract: 3rd UCL Centre for Behaviour Change Digital Health Conference 2017: Harnessing digital technology for behaviour change.
  • Bostock, S., Luik, A.I., Espie, C.A. (). Sleep and productivity benefits of digital cognitive behavioural therapy for insomnia: a randomized controlled trial conducted in the workplace environment. Journal of Sleep Research 25, suppl. 1, O372.
  • McGrath, E.R., Espie, C.A., Bostock, S., Power, A., Murphy, A.W., Newell, J., Kelly, C., Duffy, N., Gunning, P., Gibson, I., O’Donnell, M.J. (). Digital cognitive behavioural therapy for insomnia in a medical population: evidence from the sleep to lower elevated blood pressure trial (SLEPT). Journal of Sleep Research 25, suppl. 1, P132.
  • Bostock, S., Baldwin, N., Chisnall, L., Hames, P., Espie, C.A., Luik, A.I. (). Can digital CBT for insomnia address poor mental health? A cohort study within a UK mental health service. Worldsleep, 681.
  • Palagini, L., Ragno, G., Gronchi, A., Mazzei, I., Mauri, M., Terzaghi, M., Kyle, S.D., Espie, C.A., Manni, R. (). Discriminant validity and other psychometric properties of the sleep condition indicator a new tool to evaluate insomnia disorder in routine clinical practice. Worldsleep, 56.
  • Espie, C.A., Detre, G., Paluzzi, B., Kyle S.D. (). Cognitive factors predict sleep complaint across the insomnia phenotypes in young adults: the utility of data gathered using a smartphone App. Worldsleep, 73.
  • Palagini, L., Caccavale, G., Ragno, A., Gronchi, M. ,Terzaghi, M., Mauri, S. Kyle, S.D., Espie, C.A., Manni, R. (). Italian validation of the sleep condition indicator, a clinical screening tool to evaluate insomnia disorder according to DSM-5 criteria: Preliminary results. Sleep Medicine, 16: S245-246.

Conference presentations

  • Espie, C.A., Bostock, S., Kyle, S.D., Paluzzi, B., Hames, P. Associations between insomnia phenotype and chronicity with weekly treatment response during online CBT­I: observations within a large online treatment cohort. Presented at SLEEP 2014, Minneapolis, published in SLEEP 37, Suppl. A176 .
  • Bostock, S., Gollancz, R., Paluzzi, B., Hames, P., Espie, C.A. Challenging the 1% rule: an observational study of online community engagement in users of a digital sleep improvement programme. Presented at ISRII Meeting, Valencia, .
  • Coulson, N., Smedley, R., Bostock, S., Kyle, S.D., Gollancz, R., Hames, P., Espie, C.A. The pros and cons of getting engaged: users’ perspectives on the therapeutic role of Sleepio’s online community. Presented at ISRII Meeting, Valencia, .
  • Espie, C.A. The contribution of interactive sleep apps to engagement with and care of people with persistent sleep problems: experience since the launch of the sleepio app. Presented at SLEEP, Seattle, .

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